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Preclinical efficacy and safety studies designed for better drug-development decisions

IPS Therapeutique helps sponsors design, execute, interpret, and position preclinical studies within integrated testing strategies. Our flexible, collaborative approach combines scientific rigor, clear communication, and practical development insight to move programs forward efficiently.

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More than model execution 

A strong preclinical study is not only about running a model. It is about asking the right questions, selecting the right endpoints, executing the study rigorously, and interpreting the results in the context of the therapeutic program.

Design

Mechanism-driven model selection, treatment timing, route of administration, controls, and endpoint strategy.

Execute

Rodent, rabbit, and pig studies conducted with scientific rigor, practical flexibility, and clear communication.

Interpret

Integrated analysis of functional, biochemical, histological, and translational data.

Advance

Cost-conscious recommendations to help sponsors make the next development decision.

Cardiovascular Models

Heart failure, myocardial infarction, ischemia-reperfusion, TAC, hemodynamics, echocardiography, telemetry, and PV loops.

Respiratory Models

COPD, allergic asthma, IPF, ARDS-relevant acute lung injury, BALF, lung function, and histology.

Pulmonary Hypertension Models

SuHx, MCT, RV function, pulmonary pressure, vascular remodeling, and treatment response.

Fibrosis & Inflammation Models

Lung, liver, kidney, cardiac, and tissue fibrosis with inflammation, remodeling, collagen, and histology endpoints.

In-Vitro / Cell-based screening Models

Primary cells and cell lines metabolism, proliferation, secretion, gene expression assays. Screening and mechanistic investigations

Coagulation & Safety Models

Coagulation, thrombosis, hemodynamics, cardiovascular function, and tolerability assessments.

Preclinical models across major therapeutic areas

Disease-relevant models with study designs adapted to the compound, mechanism of action, route of administration, and development stage.

Have a therapeutic hypothesis to test?

IPST scientists help design the right preclinical study, select the right endpoints, and generate decision-ready data.

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