Vascular and cardiovascular diseases

Cardiovascular diseases (CVDs) underlie the core of IPST’s service portfolio. Our robust, predictive animal models of arrhythmia and left or right ventricular failure have successfully supported marketed drugs since 1999.

Call IPST 1-819-820-1515

Heart failure model: CLP sepsis

Heart failure model: Anthracyclin toxicity

Induction of arrhythmias by overpacing

Volume overload induced by aorto-caval shunt

Pressure overload induced by high-salt diet

Hypertrophic cardiomyopathy induced by trans-aortic banding (pressure overload)

Volume overload induced by aortic/pulmonary valve endocarditis

Ischemia reperfusion

Type 2 Diabetes Cardiomyopathy

Isolated Heart (Langendorff)

Ionic Current measurements

Monocrotaline-induced pulmonary hypertension

Sugen-Hypoxia-induced pulmonary arterial hypertension

Cardiac Action Potential Kinetics (APD)

Immune Thrombocytopenia (ITP)

Cerebral ischemia (stroke)

Dual-pressure implanted telemetry animals

Acute pulmonary hypertension

hERG Inhibition Assay

Let’s talk

At IPST we believe each study is worthy of tailored protocols designed to maximize the scientific and strategic value of the data generated. We believe in taking ownership of the studies entrusted to IPST while ensuring mutual collaboration for developing and agreeing to overall project plans.

01 / Cardiovascular

Cardiovascular diseases

We leverage our world-class expertise on cardiovascular diseases, e.g., pulmonary arterial hypertension, myocardial infarction, hemorrhagic shock, acute kidney injury, to craft tailored protocols designed in collaboration with you.

02 / Inflammatory

Inflammatory disorders

We leverage our world-class expertise on inflammatory disorders, e.g., diabetes, obesity, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, liver fibrosis, cholestatic liver disease, to craft tailored protocols designed in collaboration with you.

03 / Respiratory

Respiratory diseases

We leverage our world-class expertise on respiratory diseases e.,g., chronic obstructive pulmonary disease, asthma, allergic rhinitis, pulmonary fibrosis, to craft tailored protocols designed in collaboration with you.

04 / Bleeding

Bleeding disorders

We leverage our world-class expertise on bleeding disorders, e.g., hemophilia, sickle cell anemia, immune thrombocytopenia, von Willebrand disease, to craft tailored protocols designed in collaboration with you.